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Soluble TNF Receptor Type I Recombinant Protein (0.005 mg)

Soluble TNF Receptor Type I Recombinant Protein (0.005 mg)

TNFR1 belongs to the TNFR superfamily of transmembrane proteins, and is expressed in most cell types. Binding of either TNF-alpha or TNF-beta to TNFR1 initiates a signal transduction pathway that results in the activation of the transduction factor NFkappaB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells induce apoptosis. Soluble TNF Receptor I (sTNFR1) is capable of inhibiting TNF-alpha and TNF-beta activities by acting as a decoy receptor that serves as a sink for the TNF ligands. Recombinant human sTNFR1 is an 18.3 kDa protein (162 amino acid residues) comprising the cysteine rich ligand binding portion of the extracellular domain of the TNFR1 protein.

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SPECIFICATIONS

Size

0.005 mg

Presku

OPPB00201

Alternative Names

Soluble Tumor Necrosis Factor type I; TNFRSF1A; TNFAR; TNF-R55; TNFR60; p55; CD120a

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