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SOCS-3 Antibody

SOCS-3 Antibody

Cat no: 250863

Supplier: ABBIOTEC
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Suppressor of cytokine signaling (SOCS) family proteins are involved in a negative feedback system that regulates cytokine signal transduction. SOCS-3 is involved in negative regulation of cytokines through the JAK/STAT signaling pathway by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL-12, GCSF and leptin receptors. Genetic variation in the promoter region of SOCS-3 is associated with susceptibility to atopic dermatitis 4 (eczema).
Catalogue number: 250863
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: O14543
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human SOCS-3.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Suppressor of cytokine signaling 3; SOCS-3; Cytokine-inducible SH2 protein 3; CIS-3; STAT-induced STAT inhibitor 3; SSI-3; SOCS3; CIS3; SSI3
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