Reactivities: | Human |
Presku: | AAP45419 |
Size: | 100ug |
Weight: | 65kDa |
Gene: | 6646 |
Format: | Lyophilized powder |
Target: | Acyl-coenzyme A:cholesterol acyltransferase (ACACT; EC 2.3.1.26) is an intracellular protein located in the endoplasmic reticulum that forms cholesterol esters from cholesterol. Accumulation of cholesterol esters as cytoplasmic lipid droplets within macrophages and smooth muscle cells is a characteristic feature of the early stages of atherosclerotic plaques (Cadigan et al., 1988 [PubMed 3335499]). |
Alternative names: | ACACT; ACAT; ACAT1; RP11-215I23.2; SOAT; STAT |