So, Xenopus/Amphibian,2 Antibody

Transcription factor SO, Xenopus/Amphibian,-2 (So, Xenopus/Amphibian,2) forms a trimeric comple, Xenopus/Amphibian, with OCT4 on DNA and controls the e, Xenopus/Amphibian,pression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ,Zebrafish/Fish,P206. Defects in So, Xenopus/Amphibian,2 are the cause of microphthalmia syndromic type 3 (MCOPS3). Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases,Mouse,icrophthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. POU5F1/OCT4, So, Xenopus/Amphibian,2,Mouse,YC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differentiated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells. iPS cells e, Xenopus/Amphibian,hibit the morphology and growth properties of ES cells and e, Xenopus/Amphibian,press ES cell marker genes.