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Snf8 (SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) ) Blocking Peptide (the N terminal of Snf8)(100ug)

Snf8 (SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) ) Blocking Peptide (the N terminal of Snf8)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Snf8 Antibody (ARP32857_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Rat
Presku: AAP32857
Size: 100ug
Weight: 28kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: Snf8 is required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is a component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL.
Alternative names: D11moh34; MGC105799; RGD1310144
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