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SNF8 (SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)) Blocking Peptide (the middle region of SNF8)(100ug)

SNF8 (SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)) Blocking Peptide (the middle region of SNF8)(100ug)

This is a synthetic peptide designed for use in combination with anti-SNF8 Antibody(ARP57950_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum

Format

Lyophilized powder

Presku

AAP57950

Target

ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor.

Weight

29kDa

Gene Id

11267

Alternative Names

Dot3; EAP30; VPS22

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