Presku: | AAP49331 |
Size: | 100 ug |
Weight: | 71kDa |
Gene: | 55512 |
Format: | Lyophilized powder |
Target: | SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. SMPD3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It probably acts as a regulator of postnatal development and participates in bone and dentin mineralization. |
Alternative names: | FLJ22593; MGC138443; NSMASE2 |