Reactivities: | Human |
Presku: | AAP57688 |
Size: | 100ug |
Weight: | 94kDa |
Gene: | 55671 |
Format: | Lyophilized powder |
Target: | SMEK1 is the regulatory subunit of serine/threonine-protein phosphatase 4.SMEK1 may regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair. |
Alternative names: | FLFL1; KIAA2010; MSTP033; smk-1; smk1 |