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SMAD6 (5H3) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253056

SMAD6 (5H3) Antibody

SMAD6 (Mothers against decapentaplegic homolog 6) protein is an antagonist of signaling by TGF-beta type 1 receptor superfamily members. It has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD. Binds to regulatory elements in target promoter regions. SMAD6 is ubiquitous in various organs, with higher levels in lung. Isoform B is up-regulated in diseased heart tissue.

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SPECIFICATIONS

Catalog Number

253056

Size

0.1 ml

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human SMAD6 e, Xenopus/Amphibian,pressed in E. coli.\r<br>\r<br>

Isotype

Mouse IgG1

Accession

O43541

Clonality

5H3

Additional Info

Mothers against decapentaplegic homolog 6; MAD homolog 6; Mothers against DPP homolog 6; SMAD family member 6; SMAD 6; Smad6; hSMAD6; MADH6; SMAD6

SUPPLIER INFO

ABBIOTEC

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