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SMAD6 (5H3) Antibody

SMAD6 (5H3) Antibody

Cat no: 253056

Supplier: ABBIOTEC
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SMAD6 (Mothers against decapentaplegic homolog 6) protein is an antagonist of signaling by TGF-beta type 1 receptor superfamily members. It has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD. Binds to regulatory elements in target promoter regions. SMAD6 is ubiquitous in various organs, with higher levels in lung. Isoform B is up-regulated in diseased heart tissue.
Catalogue number: 253056
Reactivities: Human
Applications: Western Blot
Size: 0.1 ml
Accession: O43541
Antigen: Purified recombinant fragment of human SMAD6 e, Xenopus/Amphibian,pressed in E. coli.

Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 5H3
Additional info: Mothers against decapentaplegic homolog 6; MAD homolog 6; Mothers against DPP homolog 6; SMAD family member 6; SMAD 6; Smad6; hSMAD6; MADH6; SMAD6
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