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Slc30A8 Antibody (OAPB01156)

Slc30A8 Antibody (OAPB01156)

Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of Slc30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes, but no genetic association has been found with Type 1 diabetes. Slc30A8 expression in b-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1 beta.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Presku

OAPB01156

Target

Solute carrier family 30 member 8

Alternative Names

Slc30A8; Solute carrier family 30 member 8; zinc transporter 8; ZNT8; Zn-T8

SUPPLIER INFO

Aviva Systems Biology Incorporated

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