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SLC19A1 (solute carrier family 19 (folate transporter) member 1) Blocking Peptide (100ug)

SLC19A1 (solute carrier family 19 (folate transporter) member 1) Blocking Peptide (100ug)


Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-SLC19A1 antibody (Catalogue #: ARP44167_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP44167
Size: 100 ug
Weight: 65kDa
Gene: 6573
Format: Lyophilized powder
Target: Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. SLC19A1 plays a role in maintaining intracellular concentrations of folate.Transport of folate compounds into mammalian cells can occur via receptor-mediated (see MIM 136430) or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.[supplied by OMIM].
Alternative names: CHMD, FOLT, IFC1, REFC, RFC1