Reactivities: | Human, Mouse |
Presku: | AAP62712 |
Size: | 100ug |
Weight: | 38kDa |
Gene: | 27218 |
Format: | Lyophilized powder |
Target: | Slamf1 is a high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. |
Alternative names: | 4933415F16; AA177906; CD150; CDw150; ESTM51; IPO-3; Slam |