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Ska1 (spindle and kinetochore associated complex subunit 1 ) Blocking Peptide (the middle region of Ska1)(100ug)

Ska1 (spindle and kinetochore associated complex subunit 1 ) Blocking Peptide (the middle region of Ska1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Ska1 Antibody (ARP55460_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP55460
Size: 100ug
Weight: 28kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: Ska1 is a Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. It is required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules.
Alternative names: 2810433K01Rik; AV117428
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