Presku: | AAP50589 |
Size: | 100 ug |
Weight: | 133kDa |
Gene: | 23309 |
Format: | Lyophilized powder |
Target: | SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.It also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. SIN3B also forms a complex with FOXK1 which represses transcription. |
Alternative names: | KIAA0700 |