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SIGIRR antibody - C-terminal region (ARP49664_P050)

SIGIRR antibody - C-terminal region (ARP49664_P050)

This is a rabbit polyclonal antibody against SIGIRR. It was validated on Western Blot using a cell lysate as a positive control. Aviva Systems Biology strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (info@avivasysbio.com).

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SPECIFICATIONS

Size

50ug

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Bov, Ch/Bird, ZF/Fish

Format

Lyophilized powder

Presku

ARP49664_P050

Target

SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. It attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through a TIR-TIR domain interaction with TLR4. Through its extracellular domain it interferes with the heterodimerization of Il1R1 and IL1RAP.

Weight

25kDa

Gene Id

59307

Alternative Names

MGC110992; TIR8

SUPPLIER INFO

Aviva Systems Biology Incorporated

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