Reactivities: | Human |
Presku: | AAP49040 |
Size: | 100ug |
Weight: | 53kDa |
Gene: | 6470 |
Format: | Lyophilized powder |
Target: | This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined. |
Alternative names: | CSHMT; MGC15229; MGC24556; SHMT |