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SHH (8G3) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253016

SHH (8G3) Antibody

SHH (Sonic hedgehog) is member of the hedgehog signaling pathway. SHH binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH,PorcineTC represses the constitutive signaling activity of SMO. Sonic hedgehog is an intercellular signal essential for a variety of patterning events during development, such as ventral cell fate in the neural tube and somites, and for patterning of the anterior-posterior a, Xenopus/Amphibian,is of the developing limb bud. Defects in sonic hedgehog has been implicated in eye formation disorders and holoprosencephaly, the most common structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres.

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SPECIFICATIONS

Catalog Number

253016

Size

0.1 ml

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human SHH e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

Q15465

Clonality

8G3

Additional Info

Sonic hedgehog protein; SHH; HHG-1; TPT; HHG1; HLP3; HPE3; SMMCI; TPTPS; MCOPCB5

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