Presku: | AAP58763 |
Size: | 100 ug |
Weight: | 55kDa |
Gene: | 6461 |
Format: | Lyophilized powder |
Target: | SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells. |
Alternative names: | RP11-3J10.8; bA3J10.2 |