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Products SHANK3, S69-46
| Catalogue number: | SMC-336D |
| Reactivities: | Human, Mouse |
| Hosts: | Mouse |
| Applications: | Immunohistochemistry, Immunoprecipitation, Western Blot |
| Size: | 100ug |
| Clone: | S69-46 |
| Accession: | NP_067708.1 |
| Gene: | 59312 |
| Swiss prot: | Q9JLU4 |
| Dilutions: | 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF) |
| Form: | Protein G Purified |
| Storage buffer: | PBS pH7.4, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG2B |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Scaffolds |
| Certificate of analysis: | 1ug/mL of SMC-336 was sufficient for detection of Shank3 in 10ug COS cell lysate transiently transfected with Shank3 by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
| Scientific background: | Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins (3). Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the posts |
| Alternative names: | Shank3, Prosap2 |
| References: | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Sheng M., and Kim E. (2000) Journal of Cell Science. 113: 1851-1856. 4. Schuetz G., et al. (2004) JCB. 167(5): 645-952. |
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