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SHANK2 (SH3 and multiple ankyrin repeat domains 2 ) Blocking Peptide (the C terminal of SHANK2)(100ug)

SHANK2 (SH3 and multiple ankyrin repeat domains 2 ) Blocking Peptide (the C terminal of SHANK2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-SHANK2 Antibody (ARP64053_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP64053
Size: 100ug
Weight: 126kDa
Gene: 22941
Format: Lyophilized powder
Target: This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined.
Alternative names: AUTS17, CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3
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