Presku: | AAP56546 |
Size: | 100 ug |
Weight: | 62kDa |
Gene: | 6452 |
Format: | Lyophilized powder |
Target: | SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. |
Alternative names: | 3BP2; CRBM; CRPM; FLJ42079; RES4-23 |