SH3BP2 Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)

Supplier: Aviva Systems Biology Incorporated

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Partial length SH3BP2 is expressed in E. coli.

Presku:	APL10217
Size:	200ug
Weight:	53
Gene:	6452
Target:	The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative names:	3BP2; CRBM; CRPM; 3BP-2; RES4-23; FLJ42079; FLJ54978