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SGLT1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251498

SGLT1 Antibody

Sodium/glucose cotransporter 1 (SGLT1) actively transports glucose into cells by Na+ co-transport with a Na+ to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidneys is provided by the concerted action of a low affinity, high capacity, and a high affinity low capacity Na+/glucose co-transporter arranged in series along kidney pro, Xenopus/Amphibian,imal tubules Defects in SGLT1 are the cause of congenital glucose/galactose malabsorption (GGM). GGM is an intestinal monosaccharide transporter deficiency. GGM is an autosomal recessive disorder manifesting itself within the first weeks of life. It is characterized by severe diarrhea and dehydration which are usually fatal unless glucose and galactose are eliminated from the diet.\n

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SPECIFICATIONS

Catalog Number

251498

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human SGLT1.

Isotype

Rabbit Ig

Accession

P13866

Additional Info

SGLT1; Sodium/glucose cotransporter 1; Na(+)/glucose cotransporter 1; High affinity sodium-glucose cotransporter; Solute carrier family 5 member 1; SLC5A1; NAGT

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