Home  >  Products  >  SF3B3 (splicing factor 3b, subunit 3, 130kDa) Blocking Peptide (the middle region of SF3B3)(100ug)
SF3B3 (splicing factor 3b, subunit 3, 130kDa) Blocking Peptide (the middle region of SF3B3)(100ug)

SF3B3 (splicing factor 3b, subunit 3, 130kDa) Blocking Peptide (the middle region of SF3B3)(100ug)

Supplier: Aviva Systems Biology Incorporated
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
This is a synthetic peptide designed for use in combination with anti-SF3B3 Antibody(ARP40730_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP40730
Size: 100ug
Weight: 135kDa
Gene: 23450
Format: Lyophilized powder
Target: SF3B3 is subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
Alternative names: KIAA0017; RSE1; SAP130; SF3b130; STAF130
See Full Product Listings >