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SETD7 (SET domain containing (lysine methyltransferase) 7) Blocking Peptide (100ug)

SETD7 (SET domain containing (lysine methyltransferase) 7) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-SETD7 antibody (Catalogue #: ARP48940_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP48940
Size: 100 ug
Weight: 41kDa
Gene: 80854
Format: Lyophilized powder
Target: SETD7 is a histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It plays a central role in the transcriptional activation of genes such as collagenase or insulin. It is recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. It has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins.
Alternative names: FLJ21193; KIAA1717; KMT7; SET7; SET7/9; SET9
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