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Secreted FRP-1 Recombinant Protein (0.005 mg)

Secreted FRP-1 Recombinant Protein (0.005 mg)

Secreted Frizzled Related Proteins (sFRPs) modulate WNT signaling by binding directly to WNT proteins in a manner that affects their receptor binding and signaling capabilities. sFRP-1 is a widely distributed protein that can bind directly to WNT1, WNT2, and possibly other WNT proteins, and generally exerts anti-proliferative effects consistent with activity as a WNT antagonist. It also inhibits apoptosis and has been found to be down-regulated in many solid tumors, but up-regulated in uterine leiomyomas. Recombinant human sFRP-1 is a glycosylated 283 amino acid protein containing a cysteine rich Frizzled homologous domain.

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SPECIFICATIONS

Size

0.005 mg

Presku

OPPB00127

Alternative Names

Soluble Frizzled Related Protein-1; Secreted Apoptosis Related Protein-2; SARP-2

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