Reactivities: | Human |
Presku: | AAP52296 |
Size: | 100ug |
Weight: | 111kDa |
Gene: | 11196 |
Format: | Lyophilized powder |
Target: | COPII-coated vesicles are involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway. |
Alternative names: | MSTP053; P125 |