Supplier:
Aviva Systems Biology IncorporatedSCG5 (secretogranin V (7B2 protein) ) Blocking Peptide (the N terminal of SCG5)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP63847
Target
SCG5 acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. SCG5 binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. SCG5 is also required for cleavage of PCSK2 but does not appear to be involved in its folding. SCG5 plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
Weight
23kDa
Gene Id
6447
Alternative Names
7B2; P7B2; SGNE1; SgV
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