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RUNX1T1 (runt-related transcription factor 1; translocated to, 1 (cyclin D-related)) Blocking Peptide (100ug)

RUNX1T1 (runt-related transcription factor 1; translocated to, 1 (cyclin D-related)) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-RUNX1T1 antibody (Catalogue #: ARP33996_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP33996
Size: 100 ug
Weight: 62kDa
Gene: 862
Format: Lyophilized powder
Target: RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.
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