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RTN4 (Human) cDNA (1ug)

RTN4 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human RTN4 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-RTN4 polyclonal antibody.
Presku: ANA11672
Size: 1ug
Gene: 57142
Target: This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.
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