Reactivities: | Mouse |
Presku: | AAP54682 |
Size: | 100ug |
Weight: | 32kDa |
Gene: | 16785 |
Format: | Lyophilized powder |
Target: | Rpsa is required for the assembly and/or stability of the 40S ribosomal subunit. It is also required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. It slso functions as a cell surface receptor for laminin. It plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. It may play a role in cell fate determination and tissue morphogenesis. It also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. It enables malignant tumor cells to penetrate laminin tissue and vessel barriers and activates precursor thymic anti-OFA/iLRP specific cytotoxic T cell. It may induce CD8 T-suppressor cells secreting IL-10. |
Alternative names: | 67kDa; 67lr; AL022858; Lamr; Lamr1; Lamrl1; MGC117921; MGC118614; MLR; P40; P40-3; P40-8 |