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Rpl32 (ribosomal protein L32 ) Blocking Peptide (the middle region of Rpl32)(100ug)

Rpl32 (ribosomal protein L32 ) Blocking Peptide (the middle region of Rpl32)(100ug)

This is a synthetic peptide designed for use in combination with anti-Eya4 Antibody (ARP39975_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum, Mouse

Format

Lyophilized powder

Presku

AAP39975

Target

Eya4 is a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Eya4 promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. It may be involved in development of the eye.

Weight

67kDa

Gene Id

14051

Alternative Names

B130023L16Rik

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