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Rora (par-6 (partitioning defective 6,) homolog alpha (C. elegans) ) Blocking Peptide (the middle region of Rora)(100ug)

Rora (par-6 (partitioning defective 6,) homolog alpha (C. elegans) ) Blocking Peptide (the middle region of Rora)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Rora Antibody (ARP34766_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP34766
Size: 100ug
Weight: 59kDa
Gene: 19883
Format: Lyophilized powder
Target: Rora is an orphan nuclear receptor. It binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma, in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1. IT is a possible receptor for cholesterol or one of its derivatives.
Alternative names: 9530021D13Rik; Nr1f1; ROR1; ROR2; ROR3; nmf267; sg; staggerer; tmgc26
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