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Rnls (renalase, FAD-dependent amine oxidase ) Blocking Peptide (the middle region of Rnls)(100ug)

Rnls (renalase, FAD-dependent amine oxidase ) Blocking Peptide (the middle region of Rnls)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Rnls Antibody (ARP59612_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP59612
Size: 100ug
Weight: 33kDa
Gene: 67795
Format: Lyophilized powder
Target: Rnls is a probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. It degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Alternative names: 6530404N21Rik; AI452315; AW060440; C10orf59
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