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Rnls (renalase, FAD-dependent amine oxidase ) Blocking Peptide (the middle region of Rnls)(100ug)

Rnls (renalase, FAD-dependent amine oxidase ) Blocking Peptide (the middle region of Rnls)(100ug)

This is a synthetic peptide designed for use in combination with anti-Rnls Antibody (ARP59612_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum, Mouse

Format

Lyophilized powder

Presku

AAP59612

Target

Rnls is a probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. It degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.

Weight

33kDa

Gene Id

67795

Alternative Names

6530404N21Rik; AI452315; AW060440; C10orf59

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