Reactivities: | Human |
Presku: | AAP59127 |
Size: | 100ug |
Weight: | 44kDa |
Gene: | 79589 |
Format: | Lyophilized powder |
Target: | RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. |
Alternative names: | FLJ23516; GRAIL |