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RHOB (ras homolog gene family, member B) Blocking Peptide (the middle region of RHOB)(100ug)

RHOB (ras homolog gene family, member B) Blocking Peptide (the middle region of RHOB)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-RHOB Antibody(ARP54702_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP54702
Size: 100ug
Weight: 22kDa
Gene: 388
Format: Lyophilized powder
Target: RHOB mediates apoptosis in neoplastically transformed cells after DNA damage.RHOB is not essential for development but affects cell adhesion and growth factor signaling in transformed cells.RHOB plays a negative role in tumorigenesis as deletion causes tumor formation. RHOB is involved in intracellular protein trafficking of a number of proteins.RHOB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes.RHOB is also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
Alternative names: ARH6; ARHB; MST081; MSTP081; RHOH6
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