Reactivities: | Human |
Presku: | AAP42805 |
Size: | 100ug |
Weight: | 27kDa |
Gene: | 64407 |
Format: | Lyophilized powder |
Target: | RGS18 is a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. |
Alternative names: | RGS13 |