

Supplier:
Aviva Systems Biology IncorporatedRGR antibody - N-terminal region (ARP63387_P050)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
50ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum
Format
Lyophilized powder
Presku
ARP63387_P050
Target
This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively).
Weight
32kDa
Gene Id
5995
Alternative Names
RP44
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