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REXO4 (REX4, RNA exonuclease 4 homolog (S. cerevisiae)) Blocking Peptide (100ug)

REXO4 (REX4, RNA exonuclease 4 homolog (S. cerevisiae)) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-REXO4 antibody (Catalogue #: ARP39415_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP39415
Size: 100 ug
Weight: 47kDa
Gene: 57109
Format: Lyophilized powder
Target: The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.
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