

Supplier:
Aviva Systems Biology IncorporatedRest (RE1-silencing transcription factor ) Blocking Peptide (the middle region of Rest)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Mouse
Format
Lyophilized powder
Presku
AAP38643
Target
Rest is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Rest restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Rest mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
Weight
118kDa
Gene Id
The peptide is characterized by mass spectroscopy
Alternative Names
2610008J04Rik; AA407358; MGC150099; NRSF
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