REG1A (Regenerating islet-derived 1 alpha) is a member of the Reg family of secreted proteins with a C-type lectin domain. REG1A is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Due to variable glycosylation,Porcineancreatic REG1A e, Xenopus/Amphibian,ists as multiple species of 16 -18 kDa. REG1A promotes the maintenance and growth of pancreatic islet (B)-cells and intestinal villi. It is upregulated in pancreatitis and some carcinomas. REG1A is an antigenic target in autoimmune diabetes.