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Recombinant Rat IL-2 (carrier-free)
BioLegend

Supplier:

BioLegend

Cat no: 579502

Recombinant Rat IL-2 (carrier-free)

Interleukin 2 was discovered through its function as a T cell growth factor (TCGF). IL-2 binds to IL-2 receptor which is expressed in T and B cells, thymocytes, and NK cells. The IL-2 receptor comprises three distinct components: the alpha-chain, which is cytokine specific, and the beta- and gammac-subunits which are share with the IL-15 receptor. In addition, the gammac-subunit is a component of a series of other cytokine receptors, these being members of the gammac cytokine receptor family (IL-4, IL-7, IL-9, and IL-21) (3). IL-2 signaling may play a major role in the differentiation of regulatory T cells (4). IL-2, IL-15, and IL-7 can all support NK cell differentiation; nevertheless, analyses of IL-2(-/-), IL-2Ralpha(-/-) mice fail to exhibit significant defects in NK cell development. This data suggest that IL-2 might have a redundant role in NK cell differentiation (4).

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SPECIFICATIONS

Catalog Number

579502

Size

10 microg

Gene Id

116562

Dilutions

Use when high specific biological activity is required.

Storage Temp

-20 C or -70 C

Shipping Temp

Blue Ice

Storage Buffer

Unopened vial can be stored at 4C for three months, at -20C for six months, or at -70C for one year. For maximum results, quick spin vial prior to opening. Stock solutions should be prepared at no less than 10microg/mL in buffer containing carrier protein such as 1% BSA or HSA or 10% FBS. For long term storage, aliquot into polypropylene vials and store in a manual defrost freezer. Avoid repeated freeze/thaw cycles.

Alternative Names

Interleukin-2, TCGF, EDF, KHF, MAF-CI, TDF

Regulatory Status

RUO

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

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