Nerve Growth Factor (NGF- beta ) is a neurotrophic factor related to BDNF, NT-3 and NT-4. NGF- beta acts through its receptor beta -NGFR, and is involved in the development and maintenance of the sensory and sympathetic nervous systems. NGF- beta is also involved in the growth, differentiation and survival of B lymphocytes. , and Proteins show cross-reactivity. Recombinant NGF- beta is a non-covalently linked homodimer, containing two 121 amino acid chains, with a total molecular weight of 27.2 kDa.