Macrophage Inflammatory Protein-1 beta (MIP-1 beta ), also known as CCL4, is produced by macrophages and thought to induce inflammatory responses, including superoxide production by neutrophils. MIP-1 alpha and MIP-1 beta can exist as a naturally occurring heterodimer has been shown to have antiviral activity against HSV-1. Recombinant MIP-1 beta is a nonglycosylated Protein, containing 69 amino acids, with a molecular weight of 7.9 kDa.