Interleukin-19 (IL-19) is a member of the IL-10 family produced by resting B cells and monocytes. IL-19 is thought to be up-regulated when monocytes are treated with GM-CSF or LPS. IL-19 shares a receptor complex with IL-20, and acts to induce IL-6 and TNF- alpha production by monocytes and promotes the Th2 response. Recombinant IL-19 is a nonglycosylated Protein, containing 155 amino acids, with a molecular weight of 17.9 kDa.
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