Interleukin-17E (IL-17E), also commonly called IL-25, is a pro-inflammatory cytokine member of a six-species family of Proteins (IL-17A-17F). IL-17F stimulates secretion of IL-8 and induces activation of NF-kappa B by binding to the receptor IL-17RB. Recombinant IL-17E is a non-glycosylated, disulfide-linked, homodimer, containing two 145 amino acid chains, with a total molecular weight of 35.5 kDa.
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