Fibroblast Growth Factor 4 (FGF-4) is a growth factor predominantly expressed during embryonic development, playing a key role in limb development. In culture, FGF-4 has been shown to be an important regulator of growth for stem cells, fibroblasts and endothelial cells. Unglycosylated FGF-4 is N-terminally cleaved into 13 kDa or 15 kDa Proteins that are more active than the precursor 19 kDa Protein, Bellosa P, et al. (1993). FGF-4 shares high homology and crossreactivity with the Protein. Recombinant FGF-4 is a non-glycosylated Protein containing 140 amino acids, with a total molecular weight of 15 kDa
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