Connective Tissue Growth Factor (CTGF) is a member of cysteine rich regulatory Proteins that are both mitogenic and chemotactic. Each Protein has an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain and cysteine knot region. CTGF has multiple effects on development and differentiation. Recombinant CTGF is a nonglycosylated Protein, containing 98 amino acids, with a molecular weight of 11.2 kDa