Reactivities: | Mouse |
Presku: | AAP59228 |
Size: | 100ug |
Weight: | 104kDa |
Gene: | The peptide is characterized by mass spectroscopy |
Format: | Lyophilized powder |
Target: | Reck negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. It appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression. |
Alternative names: | MGC169689; St15; mRECK |