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RDH8 (retinol dehydrogenase 8 (all-trans) ) Blocking Peptide (the middle region of RDH8)(100ug)

RDH8 (retinol dehydrogenase 8 (all-trans) ) Blocking Peptide (the middle region of RDH8)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-RDH8 Antibody (ARP65373_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP65373
Size: 100ug
Weight: 34kDa
Gene: 50700
Format: Lyophilized powder
Target: All-trans-retinol dehydrogenase (RDH8) is a visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol in the presence of NADPH (Rattner et al., 2000 [PubMed 10753906]). It is a member of the short chain dehydrogenase/reductase family and is located in the outer segments of photoreceptors; hence it is also known as photoreceptor retinol dehydrogenase. It is important in the visual cycle by beginning the rhodopsin regeneration pathway by reducing all-trans-retinal, the product of bleached and hydrolysed rhodopsin.
Alternative names: PRRDH; SDR28C2
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